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GT stands for glutamyltransferase, an enzyme that is primarily found in the cells of the liver.

GT is a liver enzyme that describes the health of the liver

GT is one of the standard tests used to assess the health of the liver and bile ducts, especially when there is suspicion of alcohol-related health issues. More GT is produced by liver cells when they are under stress, such as in liver diseases or heavy alcohol consumption.

Brief about GT

  • GT stands for glutamyltransferase and is an enzyme found in the liver.
  • Together with other liver values, the GT value indicates the general health of the liver and bile ducts.
  • A high GT value is associated with excessive alcohol consumption, liver diseases, and obesity.

What is a GT analysis?

GT stands for glutamyltransferase, an enzyme primarily found in the cells of the liver. Specifically, it is located in the cells surrounding the bile ducts where it affects several processes by catalyzing chemical reactions.

One of its most important tasks is to assist in detoxifying harmful substances, so more GT is produced with high alcohol consumption. Since GT is primarily found in cells around the bile ducts, it also increases significantly when various disease processes occur in that area.

Therefore, a GT analysis is useful both for detecting diseases in the liver and bile ducts and for assessing alcoholism and risky drinking. The GT value is examined through a standard blood test.

What are the reference values for the GT value?

Women ≤ 40 years:0,15 – 0,75 µkat/L
Women > 40 years: 0,15 – 1,2 µkat/L
Men ≤ 40 years: 0,15 – 1,3 µkat/L
Men > 40 years: 0,20 – 1,9 µkat/L

The reference values may vary depending on where the analysis is performed, and which analysis method is used.

What does a high GT value mean?

High values can occur in the following conditions:

Some individuals, especially the elderly, may sometimes have elevated liver values without any detectable cause or impact on health.

What does a low GT value mean?

A low GT value is usually harmless and expected in a healthy person. A low value indicates good liver and bile duct health.

How to interpret the GT value?

Alcohol increases the production of GT in liver cells, so a blood test can be used to assess alcohol consumption. Since the value does not always reveal everything about alcohol consumption, and some individuals also do not show the same increase in GT due to alcohol, further investigations are needed to provide a complete result.

Often, the result of an AUDIT (test to assess alcohol consumption) is combined with the result of a GT test when assessing potential alcohol abuse.

Read more about how alcohol affects health.

Linked to alcohol and weight

In general:

The GT value increases in connection with medical conditions such as liver tumors and blocked bile ducts. The value also increases slightly in hepatitis. In infectious hepatitis, GT is a good indicator of improvement as it normalizes more slowly than liver enzymes.

A single GT test does not provide much specific information. Therefore, when it comes to liver conditions, doctors always take several different liver tests whose results are weighed together. When examining the liver, ALAT, ASAT, and ALP are often taken in addition to GT, sometimes even more.

How can I affect my GT value?

There are some things you can do to improve your GT value, some are listed below:

In general, the GT value is good if you are of normal weight and do not have excessive alcohol consumption.

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