Skip to content
Home / Articles / C-reactive protein and high-sensitivity CRP (P-hsCRP) 
A man drinks from a cup.

C-reactive protein and high-sensitivity CRP (P-hsCRP) 

CRP or a high-sensitivity CRP test is usually carried out if an inflammatory disease is suspected.

CRP & High-sensitivity CRP (P-hsCRP)

  • High-sensitivity CRP can be used to assess the risk of cardiovascular diseases.
  • Even mildly elevated high-sensitivity CRP levels have been shown to be linked to an increased risk of arterial and coronary artery disease.
  • When there is no acute bacterial, viral, or other infection in the body, the result of the test can be used to assess silent inflammation. 

C-reactive protein, CRP

CRP stands for C-reactive protein. CRP is a protein produced by liver cells, the level of which increases significantly in a wide range of infections and tissue damage. The level of CRP increases as quickly as 6–12 hours from the onset of the infection, making it a very useful test for inflammation. 

The C-reactive protein test enables us to examine the inflammatory state of the body. Inflammation can arise as a result of unhealthy habits, infectious diseases caused by virus or bacteria, or issues such as autoimmune diseases or a reaction to an injury. CRP also increases in tissue damage such as heart attack.

Why is CRP tested in conjunction with ferritin measurement?

CRP is also determined alongside ferritin measurement. Ferritin levels often rise during infections or other inflammatory conditions. For this reason, when determining ferritin levels, CRP should also be measured. Generally, it is not advisable to measure ferritin during an acute febrile infection or when one still feels like being in the recovery phase.

Reference value for CRP

Reference levels may vary depending on the laboratory and the test analysis method.

Severe bacterial infections can raise the CRP levels to more than 100 mg/L. For example, in pneumonia or inflammation of the renal pelvis, the CRP value can increase to 200 mg/L, in blood poisoning, the value can reach up to 500 mg/L.

Reference value for high-sensitivity CRP (P-hsCRP) 

Assessing the risk of cardiovascular diseases using high-sensitivity CRP:

LOW RISK<1 CRP mg/L
MODERATE RISK1–3 CRP mg/L
HIGH RISK >3 CRP mg/L
POSSIBILITY OF INFLAMMATORIAL DISEASE>5 CRP mg/L

If measured during a time when the body is not fighting any acute bacterial, viral or other infections, the result of the high-sensitivity CRP test can reveal silent inflammation in the body. If the high-sensitivity CRP value is at least 2 or 3 mg/L, it may indicate silent inflammation.

An elevated value is significant if the finding is confirmed in a repeated measurement a few weeks later. A single elevated value could be due to natural variability or a false finding.

How can I get my high-sensitivity CRP tested?

You can order the P-hsCRP as a single test from Vital’s online store. Add the desired products to the shopping cart and complete all the tests at once.

What affects the CRP level?

FAQ

CRP levels begin to decrease once an inflammation or infection is under control. The exact rate depends on individual factors and the effectiveness of the treatment, but generally, CRP can significantly decrease within a few days of starting treatment.

Esophagus inflammation, or esophagitis, can manifest in many ways. Typical symptoms include difficulty swallowing, pain in the chest when swallowing, and sometimes even the backflow of food into the mouth. In more severe cases, weight loss and bloody vomiting may also occur. The severity and type of symptoms can vary depending on the cause and extent of the inflammation.

A CRP test is performed by taking a blood sample that is analyzed in a laboratory. The sampling is a quick and simple procedure that only takes a few minutes.

CRP levels can rise very high during an acute inflammation or infection. Levels can exceed 100 mg/l, and in very severe infections or inflammatory conditions, CRP can even rise above 300 mg/l.

CRP levels are considered too high when they exceed the normal reference value, which is usually below 10 mg/l. High values generally indicate inflammation or infection, and very high values (over 100 mg/l) can be a sign of a severe inflammatory condition or infection.

Inflammation values are measured with a laboratory test performed from a venous blood sample. No doctor’s referral is needed for the test, and it can be taken through Vital.

A man cycling.
Information Article

GFR (glomerular filtration rate)

GFR (Glomerular Filtration Rate) test reflects the kidneys’ ability to cleanse the blood, that is, their ability to remove excess water and waste material from the body.

A man is training.
Information Article

PSA indicates prostate health

Prostate-specific antigen, or PSA, is a protein produced in the prostate gland. The prostate is a gland that men have around the urethra, between the penis and the bladder. PSA sampling can diagnose various prostate conditions.

Go to cart: kr